Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 9/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 9/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PPP1CA | P62136 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656460 | 1.00 | FLT3 (0.48) | FLT3GSK3BF11KLKB1MIF | |
| SCHEMBL29479366 | 0.83 | F11 (0.48) | F11KLKB1 | |
| SCHEMBL21357425 | 0.83 | F11 (0.48) | F11KLKB1 | |
| SCHEMBL29089465 | 0.83 | FLT3 (0.47) | FLT3GSK3BF11KLKB1MIF | |
| SCHEMBL30656500 | 0.83 | FLT3 (0.47) | FLT3GSK3BF11KLKB1MIF | |
| SCHEMBL30656543 | 0.82 | KDR (0.44) | F11KLKB1 | |
| SCHEMBL29089485 | 0.82 | KDR (0.44) | F11KLKB1 | |
| SCHEMBL29089482 | 0.81 | F11 (0.39) | F11KLKB1 | |
| SCHEMBL30656519 | 0.81 | F11 (0.39) | F11KLKB1 | |
| SCHEMBL24633281 | 0.79 | F11 (0.50) | F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903585-A | Oxo-pyridine derivative and application thereof in medicine | 天津药物研究院有限公司 | 2023-10-20 | — | — | CN | disclosed |