Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29841679 | 1.00 | GRM2 (0.40) | GRM2PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL27085852 | 0.81 | GRM2 (0.44) | GRM2PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL32686609 | 0.78 | PIK3CD (0.38) | GRM2PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL32686323 | 0.77 | GRM2 (0.33) | GRM2PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL29238286 | 0.76 | GRM2 (0.40) | GRM2PIK3CDPIK3CBPIK3CAKDR | |
| SCHEMBL32686499 | 0.76 | CDK5 (0.41) | GRM2PIK3CDPIK3CBPIK3CAKDR | |
| SCHEMBL27085865 | 0.76 | PIM1 (0.49) | GRM2PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL32686624 | 0.76 | CLK1 (0.38) | GRM2PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL29841781 | 0.76 | HTR2A (0.38) | GRM2PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL21200175 | 0.76 | HTR2A (0.38) | GRM2PIK3CDPIK3CBPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888112-A | Lactams as CBL-B inhibitors | 基因泰克公司 | 2023-10-13 | — | — | CN | disclosed |