Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27086116 | 0.81 | PARP1 (0.43) | GRM2PARP1KDR | |
| SCHEMBL32686292 | 0.81 | GRM2 (0.35) | PIK3CDPIK3CBPIK3CAGRM2PARP1 | |
| SCHEMBL32686378 | 0.78 | PIM1 (0.38) | PIK3CDPIK3CBPIK3CAGRM2PARP1 | |
| SCHEMBL29841679 | 0.78 | GRM2 (0.40) | PIK3CDPIK3CBPIK3CAGRM2PIK3CG | |
| SCHEMBL29089792 | 0.78 | GRM2 (0.40) | PIK3CDPIK3CBPIK3CAGRM2PIK3CG | |
| SCHEMBL27085852 | 0.77 | GRM2 (0.44) | PIK3CDPIK3CBPIK3CAGRM2PIK3CG | |
| SCHEMBL32686565 | 0.76 | CBLB (0.32) | PIK3CDPIK3CBPIK3CAKDR | |
| SCHEMBL32686205 | 0.76 | DRD1 (0.38) | PIK3CDPIK3CBPIK3CAGRM2 | |
| SCHEMBL32686542 | 0.75 | PIK3CD (0.36) | PIK3CDPIK3CBPIK3CAGRM2 | |
| SCHEMBL32686624 | 0.73 | CLK1 (0.38) | PIK3CDPIK3CBPIK3CAGRM2PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709718-A1 | 6-SUBSTITUTED-3-PHENYL-ISOINDOLIN-1-ONES AS CBL-B INHIBITORS SELECTIVE OVER C-CBL | Genentech Inc. (US) | 2026-03-18 | — | — | EP | disclosed |