SCHEMBL29090318

SCHEMBL29090318

Clc1cc(Br)cc(Cl)c1Br

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NMT1 P30419 1/20 0.46
AHR P35869 4/20 0.33
CYP3A4 P08684 2/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PLAU P00749 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
GAA P10253 1/20 0.30
MAPK1 P28482 1/20 0.30
GPR35 Q9HC97 1/20 0.30
APEX1 P27695 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28667897 0.84 TDP1 (0.41) NMT1AHRCYP3A4TSHRTDP1
SCHEMBL12449520 0.80 ALDH1A1 (0.38) NMT1TSHRMEN1MAPTKMT2A
SCHEMBL13550074 0.80 NMT1 (0.38) NMT1CYP3A4GABRA1GABRB1MEN1
SCHEMBL793988 0.80 NMT1 (0.38) NMT1TDP1MEN1MAPTKMT2A
SCHEMBL10616362 0.79 TTR (0.47) AHRCYP3A4TSHRGAAMAPK1
SCHEMBL450499 0.79 ALDH1A1 (0.53) AHRCYP3A4TSHRMEN1MAPT
SCHEMBL10872330 0.79 ALDH1A1 (0.53) NMT1AHRCYP3A4TSHRTDP1
SCHEMBL1751110 0.76 NMT1 (0.50) NMT1AHRCYP3A4TSHRTDP1
SCHEMBL5354779 0.76 NMT1 (0.44) NMT1AHRCYP3A4TSHRTDP1
Boric Acid SCHEMBL2462494 0.76 CYP3A4 (0.40) NMT1AHRCYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116891399-A Preparation method of 2, 5-dibromo-1, 3-dichlorobenzene 清源创新实验室 2023-10-17 CN claimed
CN-116891399-A Preparation method of 2, 5-dibromo-1, 3-dichlorobenzene 清源创新实验室 2023-10-17 CN disclosed
CN-116891399-A Preparation method of 2, 5-dibromo-1, 3-dichlorobenzene 清源创新实验室 2023-10-17 CN disclosed
CN-116891399-A Preparation method of 2, 5-dibromo-1, 3-dichlorobenzene 清源创新实验室 2023-10-17 CN disclosed