Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29090602 | 0.83 | TGFBR1 (0.44) | EGLN1 | |
| SCHEMBL29090603 | 0.79 | EGLN1 (0.46) | EGLN1SMN1; SMN2MAPTGAATDP1 | |
| SCHEMBL1034918 | 0.72 | SMN1; SMN2 (0.50) | EGLN1SMN1; SMN2MAPTGAATDP1 | |
| SCHEMBL10900406 | 0.72 | — | — | |
| SCHEMBL25533465 | 0.70 | SMN1; SMN2 (0.42) | EGLN1SMN1; SMN2MAPTGAATDP1 | |
| SCHEMBL24424298 | 0.69 | SMN1; SMN2 (0.47) | EGLN1SMN1; SMN2MAPTGAATDP1 | |
| SCHEMBL6016763 | 0.69 | SMN1; SMN2 (0.47) | EGLN1SMN1; SMN2 | |
| SCHEMBL27490039 | 0.69 | SMN1; SMN2 (0.47) | EGLN1SMN1; SMN2 | |
| SCHEMBL22702628 | 0.69 | SMN1; SMN2 (0.44) | EGLN1SMN1; SMN2MAPTGAATDP1 | |
| SCHEMBL22693768 | 0.69 | SMN1; SMN2 (0.44) | EGLN1SMN1; SMN2MAPTGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551870-A | Spirocyclic inhibitors of hepatitis B virus | 圣拉斐尔医院有限公司 | 2022-12-30 | — | — | CN | disclosed |