Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29090598 | 0.83 | EGLN1 (0.42) | EGLN1 | |
| SCHEMBL10900406 | 0.72 | — | — | |
| SCHEMBL14334779 | 0.70 | — | — | |
| SCHEMBL18343413 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL28990908 | 0.64 | KMT2A (0.34) | — | |
| SCHEMBL23762499 | 0.63 | TGFBR1 (0.42) | TGFBR1TET2EGLN1 | |
| SCHEMBL9745667 | 0.63 | ALDH1A1 (0.41) | TGFBR1TET2EGLN1 | |
| SCHEMBL22693682 | 0.63 | TGFBR1 (0.42) | TGFBR1TET2EGLN1 | |
| SCHEMBL29131508 | 0.61 | TSHR (0.35) | TGFBR1EGLN1 | |
| SCHEMBL12694106 | 0.61 | TGFBR1 (0.55) | TGFBR1TET2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551870-A | Spirocyclic inhibitors of hepatitis B virus | 圣拉斐尔医院有限公司 | 2022-12-30 | — | — | CN | disclosed |