Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.33 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29535614 | 0.82 | POLB (0.46) | MEN1KMT2A | |
| SCHEMBL25218506 | 0.82 | POLB (0.46) | MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL29535601 | 0.79 | HRH4 (0.41) | PANK3EPHX2CYP3A4TSHRCYP2D6 | |
| Trifluoroacetic Acid SCHEMBL25230709 | 0.79 | HRH4 (0.41) | PANK3EPHX2CYP3A4TSHRCYP2D6 | |
| SCHEMBL26330928 | 0.79 | CYP2D6 (0.39) | PANK3EPHX2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL2228019 | 0.79 | PANK3 (0.58) | PANK3ALDH1A1HSD17B10MAPK1HPGD | |
| SCHEMBL14933786 | 0.71 | EPHX2 (0.51) | EPHX2ALDH1A1CYP3A4HSD17B10CYP2C19 | |
| SCHEMBL20425052 | 0.66 | PANK3 (0.60) | PANK3MAPK1MEN1KMT2A | |
| SCHEMBL15547985 | 0.66 | KMT2A (0.45) | CYP3A4CYP2C19CYP2C9MEN1KMT2A | |
| SCHEMBL8514275 | 0.65 | EPHX2 (0.45) | EPHX2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490186-A | Compounds for targeted degradation of RET | C4医药公司 | 2023-07-25 | — | — | CN | disclosed |