Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23108171 | 0.75 | GPR119 (0.52) | EPHX2MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL23108170 | 0.71 | GPR119 (0.51) | EPHX2HSD17B10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29090664 | 0.71 | PANK3 (0.40) | EPHX2MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL484881 | 0.70 | MEN1 (0.66) | MEN1KMT2AHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL2856220 | 0.68 | GAA (0.61) | MEN1KMT2AHSD17B10ALDH1A1CYP2C19 | |
| SCHEMBL23107920 | 0.67 | CYP2D6 (0.47) | EPHX2MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL14891885 | 0.64 | EPHX2 (0.64) | EPHX2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL3076557 | 0.63 | KDM4E (0.56) | MEN1KMT2AHSD17B10ALDH1A1CYP2C19 | |
| SCHEMBL9934845 | 0.62 | GRIN1 (0.57) | HSD17B10ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23107924 | 0.61 | ALDH1A1 (0.44) | MEN1KMT2AHSD17B10ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013064467-A1 | AZETIDINE COMPOUNDS, COMPOSITIONS AND THEIR USE AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | F. HOFFMANN-LA ROCHE AG (CH) | 2013-05-10 | — | — | WO | disclosed |