Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | TET3 | O43151 | 4/20 | 0.45 |
| ▸ | FBXL19 | Q6PCT2 | 4/20 | 0.45 |
| ▸ | CXXC5 | Q7LFL8 | 4/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.45 |
| ▸ | CXXC4 | Q9H2H0 | 4/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.45 |
| ▸ | TET1 | Q8NFU7 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1492751 | 0.84 | AKR1C1 (0.51) | KMT2AMEN1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL15535986 | 0.83 | OPRD1 (0.47) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL3931269 | 0.76 | KMT2A (0.71) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL19029499 | 0.75 | SMARCA2 (0.35) | SMARCA2SMARCA4PROKR1 | |
| SCHEMBL30872137 | 0.74 | TAS1R3 (0.39) | AKR1C3AKR1C2AKR1C1SMARCA2SMARCA4 | |
| SCHEMBL23779147 | 0.74 | KMT2A (0.69) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL1305563 | 0.72 | KMT2A (0.39) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL6179175 | 0.72 | PROKR1 (0.53) | KMT2AMEN1AKR1C3PROKR1 | |
| SCHEMBL3441871 | 0.71 | ALDH1A1 (0.54) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL8514674 | 0.71 | CHRM1 (0.46) | KMT2AMEN1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852584-A1 | SUBSTITUTED DIPYRIDYLAMINES AND USES THEREOF | F. Hoffmann-La Roche AG (CH) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013174780-A1 | SUBSTITUTED DIPYRIDYLAMINES AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2013-11-28 | — | — | WO | disclosed |