SCHEMBL29090674

SCHEMBL29090674

CCc1ccnc(C2CCN(C(=O)OC(C)(C)C)CC2)n1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 13/20 0.49
FAAH O00519 1/20 0.46
KDM4E B2RXH2 2/20 0.46
MAPT P10636 2/20 0.46
THRB P10828 1/20 0.46
NAMPT P43490 1/20 0.44
MEN1 O00255 1/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
KMT2A Q03164 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10324281 0.91 GPR119 (0.49) GPR119FAAHKDM4EMAPTTHRB
SCHEMBL27822180 0.89 GPR119 (0.48) GPR119FAAHKDM4EMAPTTHRB
SCHEMBL1556591 0.85 GPR119 (0.54) GPR119FAAH
SCHEMBL25121090 0.84 GPR119 (0.51) GPR119FAAHKDM4EMAPTTHRB
SCHEMBL25719736 0.84 GPR119 (0.51) GPR119FAAHKDM4EMAPTTHRB
SCHEMBL7478208 0.81 GPR119 (0.65) GPR119FAAHKDM4EMAPTTHRB
SCHEMBL1557148 0.81 GPR119 (0.49) GPR119KDM4EMAPTTHRBNAMPT
SCHEMBL27822178 0.81 GPR119 (0.47) GPR119FAAHKDM4EMAPTTHRB
SCHEMBL29899523 0.80 ACHE (0.48) GPR119FAAHKDM4EMAPTTHRB
SCHEMBL28468398 0.80 ACHE (0.48) GPR119FAAHKDM4EMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116490186-A Compounds for targeted degradation of RET C4医药公司 2023-07-25 CN disclosed