SCHEMBL29090679

SCHEMBL29090679

C1CCC(COC2CCNC2)NC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 11/20 0.39
CYP2D6 P10635 2/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
TSHR P16473 1/20 0.37
KMT2A Q03164 1/20 0.37
MLNR O43193 1/20 0.37
ABCB11 O95342 1/20 0.37
EGFR P00533 1/20 0.37
FYN P06241 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
HTR1A P08908 1/20 0.37
CHRM5 P08912 1/20 0.37
ADRA2A P08913 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
CHRM1 P11229 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29090678 1.00 LTA4H (0.39) LTA4HCYP2D6MEN1ALDH1A1LMNA
SCHEMBL7908480 0.77 CYP2D6 (0.41) LTA4HCYP2D6MEN1ALDH1A1LMNA
SCHEMBL7908483 0.77 CYP2D6 (0.41) LTA4HCYP2D6MEN1ALDH1A1LMNA
Hydrochloric Acid SCHEMBL7989933 0.76 CYP2D6 (0.40) LTA4HCYP2D6MEN1ALDH1A1LMNA
Hydrochloric Acid SCHEMBL7989937 0.76 CYP2D6 (0.40) LTA4HCYP2D6MEN1ALDH1A1LMNA
SCHEMBL6577087 0.74 SLC6A2 (0.37) CHRM2CHRM1CHRM3SLC6A2SLC6A4
SCHEMBL15166134 0.72 CHRM2 (0.41) CHRM2HTR1ACHRM1CHRM3SLC6A2
SCHEMBL492706 0.72 CHRM2 (0.41) CHRM2HTR1ACHRM1CHRM3SLC6A2
SCHEMBL1243239 0.72 CHRM2 (0.41) CHRM2HTR1ACHRM1CHRM3SLC6A2
Hydrochloric Acid SCHEMBL6578137 0.72 SLC6A2 (0.36) CHRM2CHRM1CHRM3SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116490186-A Compounds for targeted degradation of RET C4医药公司 2023-07-25 CN disclosed