Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908483 | 1.00 | CYP2D6 (0.41) | CYP2D6MEN1ALDH1A1LMNATP53 | |
| Hydrochloric Acid SCHEMBL7989937 | 0.98 | CYP2D6 (0.40) | CYP2D6MEN1ALDH1A1LMNATP53 | |
| Hydrochloric Acid SCHEMBL7989933 | 0.98 | CYP2D6 (0.40) | CYP2D6MEN1ALDH1A1LMNATP53 | |
| SCHEMBL3827632 | 0.80 | CHRNB4 (0.39) | CHRNA3CHRNB4LTA4H | |
| SCHEMBL29090679 | 0.77 | LTA4H (0.39) | CYP2D6MEN1ALDH1A1LMNATP53 | |
| SCHEMBL29090678 | 0.77 | LTA4H (0.39) | CYP2D6MEN1ALDH1A1LMNATP53 | |
| SCHEMBL18398793 | 0.75 | CHRNA3 (0.46) | CHRNA3CHRNB4LTA4H | |
| SCHEMBL14592531 | 0.73 | CHRNB4 (0.38) | ALDH1A1TP53CHRNA3CHRNB4 | |
| SCHEMBL7918053 | 0.73 | CYP2D6 (0.40) | CYP2D6MEN1ALDH1A1LMNATP53 | |
| SCHEMBL7918057 | 0.73 | CYP2D6 (0.40) | CYP2D6MEN1ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |