Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20898688 | 1.00 | SMN1; SMN2 (0.32) | SMN1; SMN2APLNR | |
| SCHEMBL23523345 | 1.00 | SMN1; SMN2 (0.32) | SMN1; SMN2APLNR | |
| SCHEMBL29090937 | 1.00 | SMN1; SMN2 (0.32) | SMN1; SMN2APLNR | |
| SCHEMBL23523344 | 1.00 | SMN1; SMN2 (0.32) | SMN1; SMN2APLNR | |
| SCHEMBL28856830 | 0.77 | NAMPT (0.35) | SMN1; SMN2 | |
| SCHEMBL20905503 | 0.72 | NR1H2 (0.49) | SMN1; SMN2 | |
| SCHEMBL12897446 | 0.72 | — | — | |
| SCHEMBL30395393 | 0.71 | GRM1 (0.37) | SMN1; SMN2APLNR | |
| SCHEMBL29138292 | 0.71 | GRIN2B (0.35) | APLNR | |
| SCHEMBL6325183 | 0.71 | CHRNB2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745291-A | N- (2- (4-cyanothiazolidin-3-yl) -2-oxoethyl) -quinoline-4-carboxamide | 阿斯利康(瑞典)有限公司 | 2023-09-12 | — | — | CN | disclosed |
| EP-3694331-B1 | INDAZOLYL-SPIRO[2.3]HEXANE-CARBONITRILE DERIVATIVES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2022-11-16 | — | — | EP | disclosed |