Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1353177 | 0.81 | KDM4E (0.51) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL30013215 | 0.81 | KDM4E (0.51) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL29091573 | 0.80 | MCHR1 (0.36) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL24009064 | 0.80 | ALDH1A1 (0.58) | ALDH1A1ADORA2BKDM1AKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL28049580 | 0.80 | KDM4E (0.50) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL29091614 | 0.78 | ALDH1A1 (0.36) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL31095284 | 0.77 | MCHR1 (0.46) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL20589786 | 0.77 | MCHR1 (0.46) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL29091620 | 0.76 | MCHR1 (0.43) | KDM4E | |
| SCHEMBL8803058 | 0.75 | KDM4E (0.56) | ALDH1A1ADORA2BKDM1AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925100-A | Substituted thiophenoquinolinone compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-10-24 | — | — | CN | disclosed |