Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29091569 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KDM4ETSHRNFKB1ENPP1 | |
| SCHEMBL29091657 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1HSD17B10MEN1 | |
| SCHEMBL29091582 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10TSHRNFKB1 | |
| SCHEMBL25376794 | 0.73 | — | — | |
| SCHEMBL29091636 | 0.73 | FGFR2 (0.37) | ALDH1A1KDM4EMAPK1HSD17B10TSHR | |
| SCHEMBL17527769 | 0.72 | L3MBTL1 (0.48) | ALDH1A1KDM4EMAPK1HSD17B10TSHR | |
| SCHEMBL23409341 | 0.70 | — | — | |
| SCHEMBL29634793 | 0.70 | — | — | |
| SCHEMBL24870471 | 0.70 | — | — | |
| SCHEMBL26624450 | 0.70 | L3MBTL1 (0.33) | ALDH1A1KDM4ENFKB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925100-A | Substituted thiophenoquinolinone compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-10-24 | — | — | CN | disclosed |