Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760298 | 0.87 | LMNA (0.43) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL824244 | 0.76 | EPHX2 (0.44) | LMNAALDH1A1KMT2AHTTKDM4E | |
| SCHEMBL24832363 | 0.75 | ALDH1A1 (0.41) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL1719896 | 0.75 | ALDH1A1 (0.44) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL786210 | 0.74 | ALDH1A1 (0.52) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL28326662 | 0.74 | ALDH1A1 (0.52) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL28259609 | 0.74 | ALDH1A1 (0.52) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| Acetic Acid SCHEMBL28210853 | 0.74 | ALDH1A1 (0.49) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL10684521 | 0.74 | ALDH1A1 (0.42) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL5132418 | 0.73 | MAPT (0.58) | LMNAALDH1A1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167024-A2 | COOLING COMPOUNDS | Givaudan SA (CH) | 2010-03-31 | — | — | EP | claimed |
| WO-2008151460-A2 | COOLING COMPOUNDS | GIVAUDAN SA (CH) | 2008-12-18 | — | — | WO | claimed |