Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLR1A | O95602 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29092378 | 0.82 | PARP1 (0.40) | PARP1PARP2CNR2CNR1ALDH1A1 | |
| SCHEMBL6310590 | 0.78 | CNR2 (0.62) | PARP1PARP2CNR2CNR1ALDH1A1 | |
| SCHEMBL6071297 | 0.69 | CNR2 (0.48) | PARP1PARP2CNR2CNR1ALDH1A1 | |
| SCHEMBL31465195 | 0.69 | PARP1 (0.43) | PARP1PARP2 | |
| SCHEMBL18040375 | 0.68 | PARP1 (0.57) | PARP1PARP2CNR2CNR1ALDH1A1 | |
| SCHEMBL487963 | 0.67 | ALDH1A1 (0.56) | PARP1PARP2ALDH1A1KDM4EMAPT | |
| SCHEMBL6302640 | 0.67 | CNR2 (0.52) | PARP1PARP2CNR2CNR1ALDH1A1 | |
| SCHEMBL22497977 | 0.67 | TYK2 (0.45) | PARP1PARP2ALDH1A1KDM4EKMT2A | |
| SCHEMBL29640687 | 0.66 | BRD4 (0.34) | CNR2CNR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL15661571 | 0.66 | PARP1 (1.00) | PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137542-B | Pyridone dicarboxamides as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2023-10-27 | — | — | CN | disclosed |