Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29092575 | 0.82 | PARP1 (0.49) | PARP1PARP2KDM4ECNR1CNR2 | |
| SCHEMBL30647220 | 0.72 | BRD4 (0.35) | PARP1PARP2SMN1; SMN2KDM4ECNR2 | |
| SCHEMBL30647145 | 0.72 | BRD4 (0.35) | PARP1PARP2SMN1; SMN2KDM4ECNR2 | |
| SCHEMBL29092183 | 0.72 | BRD4 (0.35) | PARP1PARP2SMN1; SMN2KDM4ECNR2 | |
| SCHEMBL29092592 | 0.68 | BRD4 (0.48) | SMN1; SMN2ALDH1A1BRD4 | |
| SCHEMBL21628320 | 0.64 | BRD4 (0.43) | PARP1PARP2KDM4ECNR1CNR2 | |
| SCHEMBL31227169 | 0.62 | KDM4E (0.44) | PARP1PARP2KDM4EALDH1A1MAPT | |
| SCHEMBL16417106 | 0.62 | ALDH1A1 (0.47) | PARP1PARP2KDM4EALDH1A1MAPT | |
| SCHEMBL6310590 | 0.61 | CNR2 (0.62) | PARP1PARP2SMN1; SMN2KDM4ECNR1 | |
| SCHEMBL28581846 | 0.61 | BRD4 (0.41) | PARP1PARP2SMN1; SMN2KDM4ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137542-B | Pyridone dicarboxamides as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2023-10-27 | — | — | CN | disclosed |