Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 3/20 | 0.55 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23951 | 0.98 | MAPT (0.59) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL29173072 | 0.96 | MAPT (0.58) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL28486325 | 0.96 | MAPT (0.58) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL31589404 | 0.88 | MAPT (0.51) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL12393767 | 0.85 | APP (0.69) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL8411884 | 0.85 | KDM4E (0.60) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL7852393 | 0.81 | MAPT (0.60) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL9796767 | 0.81 | LTA4H (0.55) | MAPTNPC1RAB9AKDM4EPKM | |
| SCHEMBL22280 | 0.81 | NPC1 (0.62) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL28878462 | 0.80 | RAB9A (0.60) | MAPTNPC1RAB9AKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890961-B | Preparation method of visible light catalytic arylation aza uracil | 郑州大学 | 2023-11-14 | — | — | CN | disclosed |
| CN-114805226-B | Preparation method of visible light catalytic arylation quinoxalinone compound | 郑州大学 | 2023-10-27 | — | — | CN | disclosed |