Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKBIA | P25963 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906707 | 0.80 | MAPT (0.46) | KMT2AMEN1ALDH1A1MAPTRECQL | |
| SCHEMBL2905387 | 0.80 | RECQL (0.39) | KMT2AMEN1LMNAALDH1A1L3MBTL1 | |
| SCHEMBL2907027 | 0.78 | NFKBIA (0.46) | NFKBIARELAKMT2AMEN1LMNA | |
| SCHEMBL2908752 | 0.74 | SLC2A1 (0.39) | RELAKMT2AMEN1LMNAHTT | |
| SCHEMBL7572156 | 0.72 | NFKBIA (0.64) | NFKBIARELAKMT2AMEN1LMNA | |
| SCHEMBL2906630 | 0.72 | ACP1 (0.40) | RELAKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL2904800 | 0.70 | EGFR (0.50) | ALDH1A1L3MBTL1 | |
| SCHEMBL2904767 | 0.69 | MAPT (0.38) | KMT2AMEN1LMNAALDH1A1L3MBTL1 | |
| SCHEMBL2901473 | 0.69 | NTRK1 (0.42) | RELAKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1615434 | 0.69 | NFKBIA (0.42) | NFKBIARELAKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076495-B1 | QUINOLINE DERIVATIVES WITH 5-HT-BINDING PROPERTIES | HOFFMANN LA ROCHE (CH) | 2010-08-18 | — | — | EP | claimed |