SCHEMBL2909362

SCHEMBL2909362

CC(NC(=O)c1cc(C(=O)NC(C)C2CCCCC2)cc(C(=O)NC(C)C2CCCCC2)c1)C1CCCCC1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.57
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
MMP2 P08253 2/20 0.57
CA9 Q16790 2/20 0.57
CNR2 P34972 3/20 0.54
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 3/20 0.49
HPGD P15428 3/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
P2RX7 Q99572 2/20 0.48
TAS1R3 Q7RTX0 1/20 0.48
TAS1R1 Q7RTX1 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.46
LMNA P02545 1/20 0.46
NPC1 O15118 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17865784 0.89 CNR2 (0.57) CA12CA1CA2MMP2CA9
SCHEMBL2859820 0.86 WDR5 (0.48) CA12CA1CA2MMP2CA9
SCHEMBL27666303 0.85 TAS1R3 (0.55) CA12CA1CA2MMP2CA9
SCHEMBL27666301 0.85 TAS1R3 (0.55) CA12CA1CA2MMP2CA9
SCHEMBL22972220 0.84 CNR2 (0.46) CA12CA1CA2MMP2CA9
SCHEMBL3141224 0.84 POLB (0.61) CA12CA1CA2MMP2CA9
SCHEMBL3144661 0.83 CA12 (0.48) CA12CA1CA2MMP2CA9
SCHEMBL13304121 0.83 CNR2 (0.45) CA12CA1CA2MMP2CA9
SCHEMBL23130344 0.82 IDO1 (0.58) CNR2CYP2C9CYP2C19P2RX7TAS1R3
SCHEMBL2307745 0.81 CNR2 (0.51) CA12CA1CA2MMP2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732198-B2 Mono- and multi-layer blown films BASF SE (DE) 2017-08-15 US disclosed
US-20170081486-A1 Mono- and Multi-Layer Blown Films BASF SE (DE) 2017-03-23 US disclosed
US-20160136871-A1 Mono- and Multi-Layer Blown Films BASF SE (DE) 2016-05-19 US disclosed
US-9278487-B2 Mono-and multi-layer blown films BASF SE (DE) 2016-03-08 US disclosed
US-20130161875-A1 MONO-AND MULTI-LAYER BLOWN FILMS BASF SE (DE) 2013-06-27 US disclosed
EP-2026965-B1 MONO- AND MULTI-LAYER BLOWN FILMS BASF SE (DE) 2010-09-01 EP disclosed
US-20090208718-A1 Mono-and multi-layer blown films CIBA CORP. 2009-08-20 US disclosed