Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | RECQL | P46063 | 2/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | PLEC | Q15149 | 1/20 | 0.74 |
| ▸ | DRD2 | P14416 | 5/20 | 0.69 |
| ▸ | DRD3 | P35462 | 5/20 | 0.69 |
| ▸ | HTR2B | P41595 | 5/20 | 0.69 |
| ▸ | HTR6 | P50406 | 5/20 | 0.69 |
| ▸ | HTR2A | P28223 | 5/20 | 0.69 |
| ▸ | HTR1A | P08908 | 4/20 | 0.69 |
| ▸ | DRD4 | P21917 | 4/20 | 0.69 |
| ▸ | DRD5 | P21918 | 4/20 | 0.69 |
| ▸ | HTR1D | P28221 | 4/20 | 0.69 |
| ▸ | HTR1E | P28566 | 4/20 | 0.69 |
| ▸ | HTR7 | P34969 | 4/20 | 0.69 |
| ▸ | HRH1 | P35367 | 4/20 | 0.69 |
| ▸ | HTR5A | P47898 | 4/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183687 | 0.96 | KDM4E (0.80) | KDM4EMEN1KMT2AMAPTRECQL | |
| SCHEMBL29473364 | 0.96 | KDM4E (0.80) | KDM4EMEN1KMT2AMAPTRECQL | |
| SCHEMBL1162252 | 0.96 | KDM4E (0.80) | KDM4EMEN1KMT2AMAPTRECQL | |
| SCHEMBL12951376 | 0.96 | KDM4E (0.80) | KDM4EMEN1KMT2AMAPTRECQL | |
| SCHEMBL11533855 | 0.96 | KDM4E (0.80) | KDM4EMEN1KMT2AMAPTRECQL | |
| SCHEMBL1371966 | 0.96 | KDM4E (0.80) | KDM4EMEN1KMT2AMAPTRECQL | |
| Ammonia Solution, Strong SCHEMBL5792359 | 0.95 | KDM4E (0.79) | KDM4EMEN1KMT2AMAPTRECQL | |
| Water SCHEMBL11245600 | 0.95 | KDM4E (0.79) | KDM4EMEN1KMT2AMAPTRECQL | |
| Hydrochloric Acid SCHEMBL31443171 | 0.95 | KDM4E (0.79) | KDM4EMEN1KMT2AMAPTRECQL | |
| Ammonia Solution, Strong SCHEMBL26970704 | 0.95 | KDM4E (0.79) | KDM4EMEN1KMT2AMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693338-A | Polymer conjugates of drugs targeting 5-HT and other receptors in the Central Nervous System (CNS) and also targeting receptors outside the CNS | 阿伯门蒂斯有限责任公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-116964224-A | Regulation of LSD dosing using genotyping or phenotyping | 巴塞尔大学医院 | 2023-10-27 | — | — | CN | disclosed |