SCHEMBL29094073

SCHEMBL29094073

Cc1[nH]c2ccc(Cl)cc2c1C1=CC(=O)C=CC1=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR6 P51684 1/20 0.66
HKDC1 Q2TB90 1/20 0.66
LMNA P02545 1/20 0.48
MAP3K14 Q99558 2/20 0.47
PTPN11 Q06124 1/20 0.47
CYP1A2 P05177 1/20 0.47
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.47
HTR6 P50406 5/20 0.46
HTR7 P34969 2/20 0.46
MAPT P10636 1/20 0.46
HTR1B P28222 1/20 0.46
HTR2A P28223 1/20 0.46
HTR2C P28335 1/20 0.46
HTR3A P46098 1/20 0.46
CDC25A P30304 1/20 0.44
CDC25C P30307 1/20 0.44
CHEK1 O14757 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6095647 0.86 CCR6 (0.69) CCR6HKDC1LMNAGAAHPGD
SCHEMBL29094076 0.82 HKDC1 (0.64) CCR6HKDC1LMNAHPGDHTR6
SCHEMBL29094069 0.80 CCR6 (1.00) CCR6HKDC1LMNACYP1A2GAA
SCHEMBL29094064 0.75 CCR6 (0.66) CCR6HKDC1LMNAHPGDHTR6
SCHEMBL6094704 0.73 LMNA (0.46) LMNAMAP3K14CYP1A2GAAHPGD
SCHEMBL7230887 0.71 LMNA (0.50) LMNAMAP3K14CYP1A2GAAHPGD
SCHEMBL27721368 0.71 PTPN11 (0.56) MAP3K14PTPN11CYP1A2HTR6HTR7
SCHEMBL6094945 0.71 MAP3K14 (0.44) LMNAMAP3K14CYP1A2GAAHPGD
SCHEMBL9269177 0.70 MAP2 (0.62) CYP1A2HPGDHTR6HTR7MAPT
SCHEMBL29094067 0.69 CCR6 (0.65) CCR6HKDC1LMNAGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116924960-A Method for synthesizing 3-indolyl benzoquinone compound 郑州大学 2023-10-24 CN disclosed