Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 2/20 | 0.50 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.43 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.43 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.43 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MMP2 | P08253 | 4/20 | 0.41 |
| ▸ | MMP9 | P14780 | 4/20 | 0.41 |
| ▸ | MMP8 | P22894 | 4/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28002967 | 0.92 | MAPT (0.46) | NPBWR1MAPTMMP2MMP9MMP8 | |
| SCHEMBL28461432 | 0.85 | MAPT (0.41) | NPBWR1MAPTMMP2MMP9MMP8 | |
| SCHEMBL28451304 | 0.85 | MAPT (0.41) | NPBWR1MAPTMMP2MMP9MMP8 | |
| SCHEMBL28448581 | 0.85 | MAPT (0.41) | NPBWR1MAPTMMP2MMP9MMP8 | |
| SCHEMBL27762734 | 0.85 | MAPT (0.41) | NPBWR1MAPTMMP2MMP9MMP8 | |
| SCHEMBL27945170 | 0.84 | MAPT (0.40) | NPBWR1MAPTMMP2MMP9MMP8 | |
| SCHEMBL27995492 | 0.84 | MAPT (0.40) | NPBWR1MAPTMMP2MMP9MMP8 | |
| Nitrobenzene SCHEMBL27922730 | 0.83 | LMNA (0.50) | NPBWR1MAPTMMP2MMP9MMP8 | |
| Nitric Acid SCHEMBL10609842 | 0.82 | STAT3 (0.34) | NPBWR1MAPTMMP2MMP9MMP8 | |
| SCHEMBL28078978 | 0.81 | POLB (0.54) | MAPTRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521470-B | N-chloro zirconium-porphyrin MOF, N-chloro zirconium-porphyrin MOF/polymer composite material and preparation method | 中国人民解放军国防科技大学 | 2023-10-31 | — | — | CN | disclosed |