Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrobenzene SCHEMBL27922730 | 0.85 | LMNA (0.50) | POLBL3MBTL1LMNAMAPTALDH1A1 | |
| SCHEMBL28002967 | 0.85 | MAPT (0.46) | POLBMAPK1L3MBTL1LMNAMAPT | |
| SCHEMBL27676452 | 0.82 | NPC1 (0.48) | POLBMAPK1GAAMAPTTDP1 | |
| P-Nitrophenol SCHEMBL29094955 | 0.81 | NPBWR1 (0.50) | POLBLMNAGAAMAPTTDP1 | |
| Benzophenone SCHEMBL28231509 | 0.78 | POLB (0.82) | POLBMAPK1SRD5A2CES2CES1 | |
| SCHEMBL229627 | 0.78 | POLB (0.82) | POLBMAPK1SRD5A2CES2CES1 | |
| SCHEMBL28451304 | 0.78 | MAPT (0.41) | POLBMAPK1L3MBTL1LMNAMAPT | |
| SCHEMBL28448581 | 0.78 | MAPT (0.41) | POLBMAPK1L3MBTL1LMNAMAPT | |
| SCHEMBL28461432 | 0.78 | MAPT (0.41) | POLBMAPK1L3MBTL1LMNAMAPT | |
| SCHEMBL27762734 | 0.78 | MAPT (0.41) | POLBMAPK1L3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105778897-B | PH sensitive fluorescence dyes and its preparation method and application | 湖南大学 | 2017-12-26 | — | — | CN | claimed |
| CN-106905538-A | A kind of zinc-containing metal organic framework materials and its preparation method and application | 浙江省农业科学院 | 2017-06-30 | — | — | CN | claimed |
| CN-105778897-A | PH sensitive fluorochrome and preparation method and application thereof | 湖南大学 | 2016-07-20 | — | — | CN | claimed |
| CN-105778897-B | PH sensitive fluorescence dyes and its preparation method and application | 湖南大学 | 2017-12-26 | — | — | CN | disclosed |
| CN-106959279-A | A kind of metal-organic framework materials of PCN 222 and its preparation method and application | 浙江省农业科学院 | 2017-07-18 | — | — | CN | disclosed |
| CN-105778897-A | PH sensitive fluorochrome and preparation method and application thereof | 湖南大学 | 2016-07-20 | — | — | CN | disclosed |