Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 13/20 | 0.74 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21437502 | 0.86 | CFD (0.79) | CFDF11TPSB2SUCNR1PLAU | |
| SCHEMBL21438100 | 0.85 | CFD (1.00) | CFDF11TPSB2SUCNR1PLAU | |
| SCHEMBL29095073 | 0.79 | CFD (0.47) | CFDF11TPSB2SUCNR1 | |
| SCHEMBL21455913 | 0.74 | CFD (0.53) | CFDF11TPSB2SUCNR1MAPT | |
| SCHEMBL21455634 | 0.73 | CFD (0.60) | CFDSUCNR1 | |
| SCHEMBL29095076 | 0.69 | CFD (0.49) | CFDF11TPSB2SUCNR1ABCB1 | |
| SCHEMBL21437375 | 0.67 | CFD (0.57) | CFDF11TPSB2SUCNR1MAPT | |
| SCHEMBL21438636 | 0.66 | CFD (0.64) | CFDF11TPSB2SUCNR1PLAU | |
| SCHEMBL21437920 | 0.66 | CFD (0.51) | CFDF11TPSB2SUCNR1PLAU | |
| SCHEMBL21437540 | 0.66 | CFD (0.72) | CFDF11TPSB2SUCNR1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164499-A | Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-112272553-B | Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2023-09-22 | — | — | CN | disclosed |