Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 13/20 | 0.47 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.37 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21437422 | 0.87 | CFD (0.50) | CFDF11TPSB2SUCNR1AVPR1B | |
| SCHEMBL21438626 | 0.86 | CFD (0.62) | CFDF11TPSB2SUCNR1AVPR1B | |
| SCHEMBL29095139 | 0.83 | CFD (0.40) | CFDF11TPSB2AVPR1BACACB | |
| SCHEMBL29095013 | 0.79 | CFD (0.74) | CFDF11TPSB2SUCNR1 | |
| SCHEMBL21455908 | 0.76 | ACACB (0.39) | CFDSUCNR1ACACBCYP1A2CYP3A4 | |
| SCHEMBL21438097 | 0.71 | CFD (0.55) | CFDF11TPSB2AVPR1BKLKB1 | |
| SCHEMBL21437634 | 0.71 | CFD (0.54) | CFDF11TPSB2KLKB1 | |
| SCHEMBL21437211 | 0.70 | MDM2 (0.42) | AVPR1BMDM2 | |
| SCHEMBL21439724 | 0.69 | CFD (0.51) | CFDF11TPSB2SUCNR1 | |
| SCHEMBL21455901 | 0.68 | MDM2 (0.45) | ACACBCYP1A2CYP3A4CYP2C9ACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164499-A | Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-112272553-B | Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2023-09-22 | — | — | CN | disclosed |