Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 5/20 | 0.34 |
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21439703 | 0.83 | HDAC1 (0.38) | HDAC1BRD4CREBBPLCKNAMPT | |
| SCHEMBL29672928 | 0.80 | BRD4 (0.47) | HDAC1BRD4CREBBPNAMPTCCKBR | |
| SCHEMBL21455698 | 0.80 | BRD4 (0.47) | HDAC1BRD4CREBBPNAMPTCCKBR | |
| SCHEMBL23616972 | 0.76 | BRD4 (0.47) | HDAC1BRD4CREBBPNAMPTCCKBR | |
| SCHEMBL29095046 | 0.74 | CFD (0.50) | HDAC1SUCNR1 | |
| SCHEMBL21455247 | 0.74 | CFD (0.47) | HDAC1BRD4CREBBPNAMPTCCKBR | |
| SCHEMBL21439052 | 0.74 | BRD4 (0.47) | HDAC1BRD4CREBBPNAMPTCCKBR | |
| SCHEMBL21438280 | 0.74 | BRD4 (0.47) | HDAC1BRD4CREBBPNAMPTCCKBR | |
| SCHEMBL30009981 | 0.74 | BRD4 (0.47) | HDAC1BRD4CREBBPNAMPTCCKBR | |
| SCHEMBL23617124 | 0.74 | BRD4 (0.52) | HDAC1BRD4CREBBPNAMPTCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164499-A | Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-112272553-B | Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2023-09-22 | — | — | CN | disclosed |