Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21438631 | 0.85 | L3MBTL1 (0.39) | CFDL3MBTL1MAPTTRIM24TRIM33 | |
| SCHEMBL3027513 | 0.82 | L3MBTL1 (0.40) | CFDL3MBTL1ALDH1A1BRD4MAPT | |
| SCHEMBL21545141 | 0.82 | BRD4 (0.42) | CFDL3MBTL1BRD4 | |
| SCHEMBL21438206 | 0.74 | PKM (0.38) | CFDL3MBTL1TRIM24TRIM33HTR6 | |
| SCHEMBL16688841 | 0.74 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1BRD4MAPT | |
| SCHEMBL3972145 | 0.72 | BRD4 (0.41) | SLC1A3SLC1A2SLC1A1L3MBTL1ALDH1A1 | |
| SCHEMBL21438208 | 0.71 | PKM (0.37) | CFDL3MBTL1TRIM24TRIM33HTR6 | |
| SCHEMBL21438001 | 0.71 | BRD4 (0.40) | L3MBTL1BRD4HSD17B1HSD17B2 | |
| SCHEMBL16520134 | 0.71 | MAPT (0.39) | L3MBTL1ALDH1A1BRD4MAPT | |
| SCHEMBL21545325 | 0.71 | BRD4 (0.40) | CFDBRD4HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164499-A | Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-112272553-B | Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2023-09-22 | — | — | CN | disclosed |