Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 4/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13448758 | 0.86 | GRM7 (0.54) | GRM7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL17086763 | 0.86 | GRM7 (0.54) | GRM7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13448757 | 0.86 | GRM7 (0.54) | GRM7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5739780 | 0.84 | ALDH1A1 (0.57) | GRM7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23003791 | 0.80 | GRM7 (0.47) | GRM7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20029953 | 0.78 | GRM7 (0.46) | GRM7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4767889 | 0.78 | PTGS2 (0.61) | GRM7KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL20130289 | 0.78 | GRM7 (0.46) | GRM7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL185702 | 0.78 | PTGS2 (0.61) | GRM7KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL1711069 | 0.78 | PTGS2 (0.61) | GRM7KMT2AMEN1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116744926-A | Compounds as inhibitors of casein kinase | 北京原基华毅生物科技有限公司 | 2023-09-12 | — | — | CN | disclosed |