Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 4/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | AHCY | P23526 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107854 | 0.84 | NOS2 (0.34) | ADORA2AADORA2BADORA1 | |
| SCHEMBL28492779 | 0.84 | NOS2 (0.34) | ADORA2AADORA2BADORA1 | |
| SCHEMBL9176115 | 0.81 | GDA (0.32) | PNP | |
| SCHEMBL25859 | 0.79 | HRH4 (0.37) | ADORA2A | |
| SCHEMBL1982408 | 0.78 | — | — | |
| SCHEMBL11222090 | 0.77 | PDPK1 (0.32) | PNP | |
| SCHEMBL16620498 | 0.77 | PDPK1 (0.50) | PNPHIF1A | |
| SCHEMBL10615800 | 0.77 | CDK1 (0.37) | ADORA2A | |
| SCHEMBL2909569 | 0.77 | PDPK1 (0.50) | PNPHIF1A | |
| SCHEMBL10357383 | 0.76 | ADORA2A (0.34) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1348707-B1 | Pyrazolo[4,3-d]pyrimidines, processes for their preparation and methods for therapy | USTAV EX BOTAN AV CR V V I I O (CZ) | 2010-08-25 | — | — | EP | disclosed |
| US-7666851-B1 | Three ring fused analogs of isoguanosine | BENNER STEVEN ALBERT | 2010-02-23 | — | — | US | disclosed |