SCHEMBL29095960

SCHEMBL29095960

O=C(OF)C(F)(F)c1ccccc1.[NaH]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 3/20 0.44
PTPN1 P18031 1/20 0.42
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
MAPT P10636 2/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40
CES1 P23141 2/20 0.39
CYP1A2 P05177 1/20 0.39
CES2 O00748 1/20 0.38
LMNA P02545 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA5A P35218 1/20 0.36
CA9 Q16790 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2451645 0.98 KCNN4 (0.45) KCNN4PTPN1ALDH1A1TSHRMAPT
Hydrochloric Acid SCHEMBL29145555 0.96 KCNN4 (0.44) KCNN4PTPN1ALDH1A1TSHRMAPT
SCHEMBL11395704 0.83 KCNN4 (0.47) KCNN4PTPN1ALDH1A1TSHRMAPT
SCHEMBL506922 0.79 KCNN4 (0.64) KCNN4PTPN1ALDH1A1TSHRMAPT
SCHEMBL27568720 0.79 KCNN4 (0.44) KCNN4PTPN1ALDH1A1TSHRMAPT
SCHEMBL8583194 0.78 KCNN4 (0.42) KCNN4PTPN1ALDH1A1TSHRMAPT
SCHEMBL28049560 0.77 CHRM3 (0.46) KCNN4ALDH1A1MAPTKMT2AMEN1
SCHEMBL11395708 0.76 KCNN4 (0.46) KCNN4PTPN1ALDH1A1TSHRMAPT
SCHEMBL28468609 0.76 KCNN4 (0.41) KCNN4PTPN1ALDH1A1TSHRMAPT
SCHEMBL17993799 0.76 KCNN4 (0.46) KCNN4PTPN1ALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730824-B Synthesis method of 2,4, 5-trifluoro phenylacetic acid 山东国邦药业有限公司 2023-10-17 CN disclosed