SCHEMBL27568720

SCHEMBL27568720

O=C(OF)C(F)(c1ccccc1)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 3/20 0.44
PTPN1 P18031 1/20 0.42
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41
CES1 P23141 3/20 0.39
CYP1A2 P05177 1/20 0.39
MAPT P10636 3/20 0.36
RAB9A P51151 2/20 0.36
KMT2A Q03164 2/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA5A P35218 1/20 0.36
CA9 Q16790 1/20 0.36
NPC1 O15118 1/20 0.36
MAPK1 P28482 1/20 0.36
MEN1 O00255 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 2/20 0.36
S1PR4 O95977 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2451645 0.81 KCNN4 (0.45) KCNN4PTPN1ALDH1A1TSHRCES1
SCHEMBL4660655 0.80 CYP1A2 (0.48) KCNN4PTPN1ALDH1A1TSHRCES1
SCHEMBL29009831 0.80 CYP1A2 (0.48) KCNN4PTPN1ALDH1A1TSHRCES1
Hydrochloric Acid SCHEMBL29145555 0.79 KCNN4 (0.44) KCNN4PTPN1ALDH1A1TSHRCES1
SCHEMBL29095960 0.79 KCNN4 (0.44) KCNN4PTPN1ALDH1A1TSHRCES1
SCHEMBL9723653 0.79 MAPT (0.43) KCNN4PTPN1ALDH1A1TSHRCES1
SCHEMBL5054007 0.79 KCNN4 (0.40) KCNN4PTPN1ALDH1A1TSHRCES1
SCHEMBL8583194 0.78 KCNN4 (0.42) KCNN4PTPN1ALDH1A1TSHRCES1
SCHEMBL5816392 0.77 POLB (0.55) ALDH1A1TSHRMAPTKMT2AMAPK1
SCHEMBL28049560 0.77 CHRM3 (0.46) KCNN4ALDH1A1MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103222021-B Charge retention medium ASAHI GLASS CO.,LTD. (JP) 2016-05-11 CN disclosed
CN-102186921-B Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2014-01-15 CN disclosed
CN-103229261-A Method for producing charge retention medium ASAHI GLASS CO LTD 2013-07-31 CN disclosed
CN-103222021-A Charge retention medium ASAHI GLASS CO LTD 2013-07-24 CN disclosed
CN-102892814-A Production method for fluorine-containing copolymer composition, coating composition, molded article and article having coating film ASAHI GLASS CO LTD 2013-01-23 CN disclosed
CN-102844389-A Coating composition for coating surface of reflective plate for solar heat collection purposes, reflective plate for solar heat collection purposes, and processes for production of the coating composition and the reflective plate ASAHI GLASS CO LTD 2012-12-26 CN disclosed
CN-102186921-A Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2011-09-14 CN disclosed
CN-100559648-C Nonaqueous electrolytic solution and the lithium secondary battery that uses it UBE INDUSTRIES (JP) 2009-11-11 CN disclosed
CN-101107745-A Nonaqueous electrolyte solution and lithium secondary battery using same UBE INDUSTRIES (JP) 2008-01-16 CN disclosed
CN-1326870-C Antibacterial amide macrocycles BAYER HEALTHCARE AG (DE) 2007-07-18 CN disclosed
CN-1675236-A Antibacterial amide macrocycles BAYER HEALTHCARE AG (DE) 2005-09-28 CN disclosed