Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17629290 | 0.83 | HPGD (0.46) | HSP90AA1HSP90AB1MAPTBRD9RXFP1 | |
| SCHEMBL30047812 | 0.83 | HPGD (0.46) | HSP90AA1HSP90AB1MAPTBRD9RXFP1 | |
| SCHEMBL26606066 | 0.81 | CA12 (0.50) | MAPTALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL26606017 | 0.80 | CXCR2 (0.51) | MAPTALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL26606067 | 0.80 | CXCR2 (0.58) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL29030128 | 0.80 | KMT2A (0.42) | HSP90AA1HSP90AB1MAPTBRD9RXFP1 | |
| SCHEMBL4414634 | 0.78 | LMNA (0.48) | HSP90AA1HSP90AB1MAPTBRD9RXFP1 | |
| SCHEMBL26606012 | 0.78 | SMN1; SMN2 (0.53) | MAPTTRPV1ALDH1A1HSD17B10POLB | |
| SCHEMBL7857421 | 0.75 | ELANE (0.46) | MAPTRXFP1ALDH1A1LMNAHPGD | |
| SCHEMBL3783723 | 0.74 | BRD9 (0.47) | HSP90AA1HSP90AB1BRD9RXFP1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969849-A | Preparation method of deuterated o-aminophenol and intermediate thereof | 上海药坦药物研究开发有限公司 | 2023-10-31 | — | — | CN | disclosed |