Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30047812 | 1.00 | HPGD (0.46) | HPGDCYP1A2CYP2C19CYP2C9NPSR1 | |
| SCHEMBL29096059 | 0.83 | HSP90AA1 (0.47) | HPGDCYP1A2CYP2C19CYP2C9NPSR1 | |
| SCHEMBL28421464 | 0.82 | CYP1A2 (0.48) | HPGDCYP1A2CYP2C19CYP2C9NPSR1 | |
| SCHEMBL4568018 | 0.81 | NLRP3 (0.55) | HPGDCYP1A2CYP2C19CYP2C9NPSR1 | |
| SCHEMBL2591785 | 0.80 | CYP1A2 (0.43) | HPGDCYP1A2CYP2C19CYP2C9NPSR1 | |
| SCHEMBL29030128 | 0.80 | KMT2A (0.42) | HPGDLMNABRD9POLBSMN1; SMN2 | |
| SCHEMBL2031546 | 0.80 | KCNMA1 (0.54) | HPGDCYP1A2CYP2C19CYP2C9POLB | |
| SCHEMBL3407965 | 0.78 | HPGD (0.49) | HPGDCYP1A2CYP2C19CYP2C9NPSR1 | |
| SCHEMBL31021765 | 0.78 | HPGD (0.49) | HPGDCYP1A2CYP2C19CYP2C9NPSR1 | |
| SCHEMBL1008737 | 0.78 | HPGD (0.49) | HPGDCYP1A2CYP2C19CYP2C9NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715892-A | Quaternary ammonium cation substituted compounds for the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-3197276-B1 | HERBICIDAL PYRIDINO-/PYRIMIDINO-THIAZOLES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| US-11470846-B2 | Herbicidal pyridino-/pyrimidino-thiazoles | SYNGENTA PARTICIPATIONS AG (CH) | 2022-10-18 | — | — | US | disclosed |
| CN-107001349-B | Herbicidal pyrido/pyrimidothiazoles | 先正达参股股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| US-20200253208-A1 | HERBICIDAL PYRIDINO-/PYRIMIDINO-THIAZOLES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-13 | — | — | US | disclosed |
| US-20170290337-A1 | Herbicidal Pyridino-/Pyrimidino-Thiazoles | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-12 | — | — | US | disclosed |
| EP-3197276-A1 | HERBICIDAL PYRIDINO-/PYRIMIDINO-THIAZOLES | Syngenta Participations AG (CH) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046078-A1 | HERBICIDAL PYRIDINO-/PYRIMIDINO-THIAZOLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170290337-A1 | Herbicidal Pyridino-/Pyrimidino-Thiazoles | PDXK, PLPBP, DDT | HPGD 191/4885CYP1A2 136/4885CYP2C19 406/4885 |
| US-11470846-B2 | Herbicidal pyridino-/pyrimidino-thiazoles | PDXK, PLPBP, DDT | HPGD 191/4885CYP1A2 136/4885CYP2C19 406/4885 |
| US-20200253208-A1 | HERBICIDAL PYRIDINO-/PYRIMIDINO-THIAZOLES | PDXK, PLPBP, DDT | HPGD 191/4885CYP1A2 136/4885CYP2C19 406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.