Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096530 | 1.00 | MAPT (0.40) | MAPTMAPK1MEN1KMT2AFBP1 | |
| SCHEMBL29096544 | 0.88 | ADORA2A (0.41) | MEN1KMT2AFBP1RAB9ANPC1 | |
| SCHEMBL29096547 | 0.88 | ADORA2A (0.41) | MEN1KMT2AFBP1RAB9ANPC1 | |
| SCHEMBL29096535 | 0.86 | ERN1 (0.45) | MAPTMAPK1MEN1KMT2AFBP1 | |
| SCHEMBL29096531 | 0.86 | ERN1 (0.45) | MAPTMAPK1MEN1KMT2AFBP1 | |
| SCHEMBL29096536 | 0.84 | ALDH1A1 (0.47) | MAPTMAPK1MEN1KMT2AFBP1 | |
| SCHEMBL29096534 | 0.84 | ALDH1A1 (0.47) | MAPTMAPK1MEN1KMT2AFBP1 | |
| SCHEMBL29096542 | 0.79 | MEN1 (0.45) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29096529 | 0.77 | TRIM24 (0.42) | MAPTMAPK1MEN1KMT2AFBP1 | |
| SCHEMBL29096527 | 0.77 | TRIM24 (0.42) | MAPTMAPK1MEN1KMT2AFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693552-A | Polycyclic dihydrobenzofuran compound and preparation method thereof | 浙江大学 | 2023-09-05 | — | — | CN | disclosed |