Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096547 | 1.00 | ADORA2A (0.41) | ADORA2ACES2CES1TRIM24TRIM33 | |
| SCHEMBL29096530 | 0.88 | MAPT (0.40) | NPC1RAB9AMEN1KMT2AFBP1 | |
| SCHEMBL29096533 | 0.88 | MAPT (0.40) | NPC1RAB9AMEN1KMT2AFBP1 | |
| SCHEMBL29096536 | 0.83 | ALDH1A1 (0.47) | ADORA2ACA1CA2NPC1RAB9A | |
| SCHEMBL29096534 | 0.83 | ALDH1A1 (0.47) | ADORA2ACA1CA2NPC1RAB9A | |
| SCHEMBL29096527 | 0.82 | TRIM24 (0.42) | TRIM24TRIM33CA1CA2NFKB1 | |
| SCHEMBL29096529 | 0.82 | TRIM24 (0.42) | TRIM24TRIM33CA1CA2NFKB1 | |
| SCHEMBL29096548 | 0.80 | ADORA2A (0.51) | ADORA2ATRIM24TRIM33CA1CA2 | |
| SCHEMBL29096545 | 0.80 | ADORA2A (0.51) | ADORA2ATRIM24TRIM33CA1CA2 | |
| SCHEMBL29096535 | 0.74 | ERN1 (0.45) | CA1CA2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693552-A | Polycyclic dihydrobenzofuran compound and preparation method thereof | 浙江大学 | 2023-09-05 | — | — | CN | disclosed |