Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | FBP1 | P09467 | 3/20 | 0.35 |
| ▸ | IAPP | P10997 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096553 | 1.00 | ERN1 (0.37) | ERN1NPSR1L3MBTL1HSP90AA1ALDH1A1 | |
| SCHEMBL29096571 | 0.79 | TLR2 (0.54) | ERN1L3MBTL1HSP90AA1ALDH1A1KMT2A | |
| SCHEMBL29096573 | 0.79 | TLR2 (0.54) | ERN1L3MBTL1HSP90AA1ALDH1A1KMT2A | |
| SCHEMBL29096527 | 0.78 | TRIM24 (0.42) | NPSR1ALDH1A1KMT2AMEN1FBP1 | |
| SCHEMBL29096529 | 0.78 | TRIM24 (0.42) | NPSR1ALDH1A1KMT2AMEN1FBP1 | |
| SCHEMBL8677538 | 0.73 | TRPA1 (0.49) | NPSR1L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8677541 | 0.73 | TRPA1 (0.49) | NPSR1L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL29096559 | 0.73 | ERN1 (0.49) | ERN1NPSR1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL29096558 | 0.73 | ERN1 (0.49) | ERN1NPSR1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL9530709 | 0.71 | ERN1 (0.38) | ERN1NPSR1L3MBTL1HSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693552-A | Polycyclic dihydrobenzofuran compound and preparation method thereof | 浙江大学 | 2023-09-05 | — | — | CN | disclosed |