Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.54 |
| ▸ | ERN1 | O75460 | 1/20 | 0.54 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.54 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096571 | 1.00 | TLR2 (0.54) | TLR2ERN1TLR1TLR6ADORA2A | |
| SCHEMBL8140581 | 0.87 | LMNA (0.52) | NPC1MEN1KMT2APOLBMAPT | |
| SCHEMBL8140582 | 0.87 | LMNA (0.52) | NPC1MEN1KMT2APOLBMAPT | |
| SCHEMBL29096562 | 0.80 | MAPT (0.42) | TLR2ERN1TLR1TLR6NPC1 | |
| SCHEMBL30567940 | 0.80 | MAPT (0.42) | TLR2ERN1TLR1TLR6NPC1 | |
| SCHEMBL29096565 | 0.80 | MAPT (0.42) | TLR2ERN1TLR1TLR6NPC1 | |
| SCHEMBL29096552 | 0.79 | ERN1 (0.37) | ERN1MEN1KMT2AHSP90AA1MAPT | |
| SCHEMBL29096553 | 0.79 | ERN1 (0.37) | ERN1MEN1KMT2AHSP90AA1MAPT | |
| SCHEMBL16973642 | 0.77 | ALDH1A1 (0.44) | NPC1MEN1KMT2APOLBMAPT | |
| SCHEMBL11739586 | 0.76 | ALDH1A1 (0.46) | ERN1CA12MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693552-A | Polycyclic dihydrobenzofuran compound and preparation method thereof | 浙江大学 | 2023-09-05 | — | — | CN | disclosed |