Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BHMT | Q93088 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958660 | 1.00 | S1PR2 (0.46) | S1PR2S1PR1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL122149 | 1.00 | S1PR2 (0.46) | S1PR2S1PR1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL584298 | 1.00 | S1PR2 (0.46) | S1PR2S1PR1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL2909705 | 1.00 | S1PR2 (0.46) | S1PR2S1PR1SLC1A2SLC1A1SLC1A3 | |
| Hydrochloric Acid SCHEMBL1199813 | 0.98 | S1PR2 (0.45) | S1PR2S1PR1SLC1A2SLC1A1SLC1A3 | |
| Hydrochloric Acid SCHEMBL3140001 | 0.98 | S1PR2 (0.45) | S1PR2S1PR1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL3967142 | 0.95 | GPR84 (0.50) | S1PR2S1PR1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL3963429 | 0.95 | GPR84 (0.50) | S1PR2S1PR1SLC1A2SLC1A1SLC1A3 | |
| Imagabalin SCHEMBL119441 | 0.89 | ALDH1A1 (0.43) | S1PR2S1PR1SLC1A2SLC1A1SLC1A3 | |
| Imagabalin SCHEMBL3961605 | 0.89 | ALDH1A1 (0.43) | S1PR2S1PR1SLC1A2SLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3651752-B1 | CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2024-11-20 | — | — | EP | disclosed |
| EP-3459958-B1 | PROCESS AND INTERMEDIATES FOR PREPARING PRODRUGS OF PYRIDONE AMIDES USEFUL AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2024-08-07 | — | — | EP | disclosed |
| EP-2069302-B1 | SUBSTITUTED PYRIDYLMETHYL BICYCLOCARBOXYAMIDE COMPOUNDS | PFIZER (US) | 2010-08-25 | — | — | EP | disclosed |
| EP-1742950-B1 | PYRAZOLO[4,3-D] PYRIMIDINES | PFIZER LTD (GB) | 2008-12-17 | — | — | EP | disclosed |