SCHEMBL29097482

SCHEMBL29097482

Fc1cc(F)cc(-c2ccc(Cl)cc2F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.42
GRM2 Q14416 1/20 0.40
DPP4 P27487 1/20 0.39
AKR1C3 P42330 2/20 0.39
AKR1C2 P52895 2/20 0.39
KMO O15229 2/20 0.39
APP P05067 2/20 0.39
PDE3B Q13370 1/20 0.39
PDE3A Q14432 1/20 0.39
EGLN2 Q96KS0 1/20 0.38
AKR1C1 Q04828 1/20 0.38
CNR1 P21554 1/20 0.38
FASN P49327 1/20 0.38
P2RX1 P51575 1/20 0.38
P2RX4 Q99571 1/20 0.38
P2RX7 Q99572 1/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
TP53 P04637 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31067155 0.83 NPC1 (0.49) GRM2APPPDE3BPDE3ACNR1
SCHEMBL20898100 0.83 NPC1 (0.49) GRM2APPPDE3BPDE3ACNR1
SCHEMBL29097686 0.83 AHR (0.42) AHRGRM2AKR1C3AKR1C2KMO
SCHEMBL31339480 0.83 AHR (0.63) AHRDPP4CNR1KDM4ENPC1
SCHEMBL23638836 0.82 GRM2 (0.49) AHRGRM2KMOEGLN2CNR1
SCHEMBL20898215 0.82 CNR1 (0.51) GRM2DPP4PDE3BPDE3AEGLN2
SCHEMBL31067089 0.82 CNR1 (0.51) GRM2DPP4PDE3BPDE3AEGLN2
SCHEMBL23638850 0.81 S100A4 (0.46) AHRGRM2KMOEGLN2TP53
SCHEMBL30598347 0.81 S100A4 (0.46) AHRGRM2KMOEGLN2TP53
SCHEMBL14926554 0.79 TTR (0.46) GRM2KMOPDE3BPDE3ACNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116948656-B Application of ionic liquid in preparation of fluoroalkyl cyclohexyl biphenyl liquid crystal compounds 河北美星化工有限公司 2024-07-09 CN disclosed
CN-116948656-A Application of ionic liquid in preparation of fluoroalkyl cyclohexyl biphenyl liquid crystal compounds 河北美星化工有限公司 2023-10-27 CN disclosed