Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 8/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29097353 | 0.86 | HPGD (0.47) | MAPTKMT2AMEN1HPGDRAB9A | |
| SCHEMBL23678332 | 0.80 | MAPT (0.58) | MAPTKMT2AMEN1HPGDRAB9A | |
| SCHEMBL20205669 | 0.80 | MAPT (0.58) | MAPTKMT2AMEN1HPGDRAB9A | |
| SCHEMBL29097616 | 0.78 | ALDH1A1 (0.50) | MAPTKMT2AMEN1HPGDRAB9A | |
| SCHEMBL29097585 | 0.78 | ALDH1A1 (0.62) | MAPTKMT2AMEN1HPGDRAB9A | |
| SCHEMBL30665404 | 0.77 | MAPT (0.47) | MAPTKMT2AMEN1HPGDRAB9A | |
| SCHEMBL29097295 | 0.73 | LMNA (0.45) | MAPTKMT2AMEN1HPGDRAB9A | |
| SCHEMBL30989926 | 0.72 | LMNA (0.40) | MAPTKMT2AMEN1HPGDRAB9A | |
| SCHEMBL1266361 | 0.72 | LMNA (0.40) | MAPTKMT2AMEN1HPGDRAB9A | |
| SCHEMBL25937578 | 0.72 | LMNA (0.40) | MAPTKMT2AMEN1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947713-A | Ring-merging compound and application thereof | 中国科学院上海药物研究所 | 2023-10-27 | — | — | CN | disclosed |