Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.65 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.65 |
| ▸ | CSF1R | P07333 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2911917 | 0.97 | KCNH2 (0.60) | KCNH2SCN5ACSF1RMEN1GAA | |
| SCHEMBL2904759 | 0.92 | KCNH2 (0.77) | KCNH2SCN5ACSF1R | |
| SCHEMBL2911553 | 0.92 | KCNH2 (0.67) | KCNH2SCN5ACSF1RMEN1GAA | |
| SCHEMBL2910208 | 0.91 | KCNH2 (0.73) | KCNH2SCN5ACSF1RMEN1GAA | |
| SCHEMBL2905267 | 0.91 | KCNH2 (0.65) | KCNH2SCN5ACSF1RMEN1GAA | |
| SCHEMBL2907886 | 0.91 | KCNH2 (0.67) | KCNH2SCN5ACSF1RMEN1GAA | |
| SCHEMBL2910148 | 0.88 | KCNH2 (0.69) | KCNH2SCN5ACSF1RMEN1GAA | |
| SCHEMBL2912423 | 0.88 | KCNH2 (0.84) | KCNH2SCN5ACSF1RMEN1GAA | |
| SCHEMBL2914419 | 0.88 | KCNH2 (0.56) | KCNH2SCN5ACSF1RMEN1GAA | |
| SCHEMBL2912865 | 0.88 | KCNH2 (0.67) | KCNH2SCN5ACSF1RMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010496-B1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-08-25 | — | — | EP | disclosed |