Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.44 |
| ▸ | GLP1R | P43220 | 13/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29097983 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPK1ACSS2GLP1RGAA | |
| SCHEMBL30199689 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPK1ACSS2GLP1RGAA | |
| SCHEMBL25005475 | 0.90 | ACSS2 (0.47) | ALDH1A1MAPK1ACSS2GLP1R | |
| SCHEMBL30680763 | 0.90 | ALDH1A1 (0.45) | ALDH1A1MAPK1ACSS2GLP1RGAA | |
| SCHEMBL29668513 | 0.90 | ACSS2 (0.47) | ALDH1A1MAPK1ACSS2GLP1R | |
| SCHEMBL31223891 | 0.89 | GLP1R (0.44) | ALDH1A1MAPK1ACSS2GLP1R | |
| SCHEMBL20279928 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MAPK1ACSS2GLP1RMEN1 | |
| SCHEMBL20288032 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MAPK1ACSS2GLP1RMEN1 | |
| SCHEMBL29491182 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MAPK1ACSS2GLP1RMEN1 | |
| SCHEMBL30513859 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MAPK1ACSS2GLP1RMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-B | Parallel ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |