Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | F10 | P00742 | 10/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | STS | P08842 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098045 | 0.87 | F10 (0.52) | HRH3F10PLGSTSESR1 | |
| SCHEMBL30199265 | 0.86 | NR1H2 (0.53) | CYP11B2HRH3F10STSESR1 | |
| SCHEMBL30199440 | 0.86 | NR1H2 (0.53) | CYP11B2HRH3F10STSESR1 | |
| SCHEMBL29097937 | 0.86 | NR1H2 (0.53) | CYP11B2HRH3F10STSESR1 | |
| SCHEMBL29097925 | 0.80 | HRH3 (0.49) | HRH3F10NPC1POLBRAB9A | |
| SCHEMBL27197550 | 0.80 | HRH3 (0.64) | HRH3NPC1POLBRAB9AGFER | |
| SCHEMBL29098091 | 0.80 | F10 (0.51) | HRH3F10PLGNPC1RAB9A | |
| SCHEMBL23537968 | 0.78 | ESR1 (0.46) | HRH3F10PLGESR1NPC1 | |
| SCHEMBL29097949 | 0.78 | HRH3 (0.43) | HRH3F10PLG | |
| SCHEMBL23701473 | 0.77 | HRH3 (0.42) | HRH3F10PLGESR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |