Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.52 |
| ▸ | STS | P08842 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29097997 | 0.87 | CYP11B2 (0.46) | F10STSESR1HRH3SMN1; SMN2 | |
| SCHEMBL30199547 | 0.85 | NR1H2 (0.55) | F10STSESR1HCRTR2HTR2A | |
| SCHEMBL27197550 | 0.84 | HRH3 (0.64) | KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL23537968 | 0.82 | ESR1 (0.46) | F10ESR1HRH3PLG | |
| SCHEMBL29097949 | 0.82 | HRH3 (0.43) | F10HRH3PLG | |
| SCHEMBL29098091 | 0.81 | F10 (0.51) | F10HRH3PLG | |
| SCHEMBL23701473 | 0.81 | HRH3 (0.42) | F10ESR1HRH3PLG | |
| SCHEMBL29097926 | 0.81 | F10 (0.51) | F10KDM4EHRH3SMN1; SMN2HPGD | |
| SCHEMBL29097973 | 0.81 | HRH3 (0.55) | HRH3 | |
| SCHEMBL29097925 | 0.80 | HRH3 (0.49) | F10HTTLCKHRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |