Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | GHSR | Q92847 | 5/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199440 | 1.00 | NR1H2 (0.53) | NR1H2ESR2MAPK1CYP11B2MAPT | |
| SCHEMBL30199265 | 1.00 | NR1H2 (0.53) | NR1H2ESR2MAPK1CYP11B2MAPT | |
| SCHEMBL30199547 | 0.88 | NR1H2 (0.55) | NR1H2ESR2MAPK1MAPTGPR119 | |
| SCHEMBL29097997 | 0.86 | CYP11B2 (0.46) | CYP11B2HRH3F10ESR1STS | |
| SCHEMBL30199383 | 0.83 | NR1H2 (0.53) | NR1H2ESR2MAPK1MAPTGPR119 | |
| SCHEMBL29098128 | 0.82 | GPR119 (0.58) | NR1H2ESR2MAPK1GPR119GHSR | |
| SCHEMBL30199228 | 0.82 | GPR119 (0.58) | NR1H2ESR2MAPK1GPR119GHSR | |
| SCHEMBL30199590 | 0.82 | NR1H2 (0.60) | NR1H2ESR2MAPK1GHSRHRH3 | |
| SCHEMBL23538217 | 0.82 | NR1H2 (0.54) | NR1H2ESR2MAPTGPR119HRH3 | |
| SCHEMBL30014445 | 0.82 | NR1H2 (0.54) | NR1H2ESR2MAPTGPR119HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |