Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098324 | 0.78 | CYP3A4 (0.32) | CYP3A4 | |
| SCHEMBL14635533 | 0.75 | CYP3A4 (0.45) | CYP3A4PNMTPOLBSMN1; SMN2HTR2C | |
| SCHEMBL29098262 | 0.73 | CYP3A4 (0.37) | CYP3A4PNMTPOLBSMN1; SMN2HTR2C | |
| SCHEMBL26959998 | 0.71 | CYP3A4 (0.43) | CYP3A4PNMTMELKNTRK1POLB | |
| SCHEMBL24602646 | 0.70 | CYP3A4 (0.40) | CYP3A4PNMTMELKNTRK1POLB | |
| SCHEMBL31621544 | 0.70 | CYP3A4 (0.40) | CYP3A4PNMTMELKNTRK1POLB | |
| Hydrochloric Acid SCHEMBL26914890 | 0.70 | CYP3A4 (0.43) | CYP3A4PNMTMELKNTRK1POLB | |
| SCHEMBL14635622 | 0.70 | CYP3A4 (0.44) | CYP3A4PNMTPOLBSMN1; SMN2HTR2C | |
| Hydrochloric Acid SCHEMBL26631617 | 0.69 | CYP3A4 (0.39) | CYP3A4PNMTMELKNTRK1POLB | |
| SCHEMBL25072401 | 0.65 | CHRM3 (0.40) | CYP3A4PNMTHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710440-A | Plasmin inhibitor, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-09-05 | — | — | CN | disclosed |