Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 4/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098261 | 0.78 | CYP11B2 (0.34) | CYP3A4POLBSMN1; SMN2 | |
| SCHEMBL4774263 | 0.76 | DRD2 (0.43) | CYP3A4HTR2CPOLBSMN1; SMN2PNMT | |
| SCHEMBL29098269 | 0.76 | CYP3A4 (0.41) | CYP3A4HTR2CPOLBSMN1; SMN2PNMT | |
| Hydrochloric Acid SCHEMBL26631614 | 0.76 | CYP3A4 (0.41) | CYP3A4HTR2CF10POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL26631633 | 0.75 | CYP3A4 (0.40) | CYP3A4HTR2CPOLBSMN1; SMN2PNMT | |
| SCHEMBL29098326 | 0.73 | CYP3A4 (0.37) | CYP3A4HTR2CPOLBSMN1; SMN2PNMT | |
| SCHEMBL2904220 | 0.73 | MLNR (0.39) | CYP3A4HTR2CPOLBSMN1; SMN2PNMT | |
| SCHEMBL13090252 | 0.73 | CYP3A4 (0.38) | CYP3A4HTR2CPOLBSMN1; SMN2PNMT | |
| Hydrochloric Acid SCHEMBL2910834 | 0.72 | CHRM2 (0.38) | CYP3A4HTR2CPOLBSMN1; SMN2PNMT | |
| Hydrochloric Acid SCHEMBL2907597 | 0.72 | CYP3A4 (0.38) | CYP3A4HTR2CPOLBSMN1; SMN2PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119300824-A | Use of tetrahydronaphthyridine derivatives for preparing products for improving pigmentation | 赛诺哈勃药业（成都）有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119255801-A | Application of tetrahydronaphthyridine derivative in preparation of medicine for preventing and treating adhesion related diseases | 赛诺哈勃药业（成都）有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-116710440-A | Plasmin inhibitor, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-09-05 | — | — | CN | disclosed |