Methoxymethane

Methoxymethane

SCHEMBL29098906

COC.Nc1cc(O)c(O)c(Br)c1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.42
MAPT P10636 1/20 0.42
ALOX5 P09917 1/20 0.41
PTGS2 P35354 1/20 0.41
TSHR P16473 3/20 0.37
TDP1 Q9NUW8 3/20 0.37
CYP3A4 P08684 2/20 0.37
CASP1 P29466 2/20 0.35
ALOX15 P16050 2/20 0.35
ALOX12 P18054 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
RECQL P46063 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PTPN1 P18031 4/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30184938 0.91 GAA (0.50) GAAMAPTTSHRTDP1CYP3A4
SCHEMBL95180 0.78 CYP3A4 (0.58) GAAMAPTALOX5PTGS2TSHR
Hydrochloric Acid SCHEMBL4929431 0.76 CYP3A4 (0.55) GAAMAPTALOX5PTGS2TSHR
SCHEMBL24701452 0.73 GAA (0.46) GAAMAPTTSHRTDP1CYP3A4
SCHEMBL18751508 0.73 GAA (0.46) GAAMAPTALOX5PTGS2TSHR
SCHEMBL13963710 0.73 PTGS2 (0.50) GAAMAPTALOX5PTGS2TSHR
SCHEMBL26467101 0.73 GAA (0.46) GAAMAPTTSHRTDP1CYP3A4
SCHEMBL632547 0.72 THRB (0.50) GAAMAPTTSHRTDP1CYP3A4
SCHEMBL21695780 0.72 GAA (0.50) GAAMAPTALOX5PTGS2TSHR
SCHEMBL11589642 0.72 MAPT (0.50) GAAMAPTTSHRTDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110698352-B Synthetic method of 3-bromo-5-aminocatechol dimethyl ether 邢台学院 2023-01-17 CN claimed
CN-110698352-A Synthetic method of 3-bromo-5-aminocatechol dimethyl ether 邢台学院 2020-01-17 CN claimed
CN-110698352-B Synthetic method of 3-bromo-5-aminocatechol dimethyl ether 邢台学院 2023-01-17 CN disclosed
CN-110698352-B Synthetic method of 3-bromo-5-aminocatechol dimethyl ether 邢台学院 2023-01-17 CN disclosed
CN-110698352-B Synthetic method of 3-bromo-5-aminocatechol dimethyl ether 邢台学院 2023-01-17 CN disclosed
CN-110698352-A Synthetic method of 3-bromo-5-aminocatechol dimethyl ether 邢台学院 2020-01-17 CN disclosed
CN-110698352-A Synthetic method of 3-bromo-5-aminocatechol dimethyl ether 邢台学院 2020-01-17 CN disclosed
CN-110698352-A Synthetic method of 3-bromo-5-aminocatechol dimethyl ether 邢台学院 2020-01-17 CN disclosed